The possibility was last touted in 2010 by former Giro d'Italia director Angelo Zomegnan, who attended a reception at the Italian embassy in Washington, DC for a project to bring the race there in 2012. The city was considered a front runner out of three candidates, but faded after the DC Mayor Adrien Fenty lost his re-election bid and Zomegnan was removed as race director.

However, it would appear that the success of the Giro d'Italia's start in Israel, the first ever outside Europe, has revived the debate about the idea of a start on the other side of the Atlantic. Vegni also discussed the Giro's Grande Partenza in Israel with RAI, pronouncing it a success. "I was very convinced this adventure could work, I knew the [organising committee in Israel] when they came over here, and I can say our bet has been won.