Italy added testing and self-isolation requirements for American travelers on the heels of the European Union removing the USA from its safe travel list. Though the most dramatic policy changes affect unvaccinated travelers – who are still welcome to enter the country, so long as they take the time to self-isolate – vaccinated travelers will have to jump through additional hoops of new testing requirements.

All travelers who have been in the USA in the past 14 days are subject to Italy's heightened protocols before entry. All travelers, regardless of vaccination status, must: 1) Take a molecular or antigenic swab coronavirus test and get a negative result within 72 hours before arrival. Children under 6 are exempt. 2) Fill out a digital passenger locator form, which aids contact tracing efforts if a traveler is exposed to COVID-19 during a trip.