Maria Manca was born in Ozieri (Sassari) in 1982 and graduated from the "Università per Stranieri di Perugia" in 2008 with a degree in International Relations. In 2010 she entered the Diplomatic career of the Italian Ministry of Foreign Affairs.

Her first assignment was to the office of the Directorate General for Development and Cooperation of the Italian Ministry of Foreign Affairs in Rome, Italy. From 2013 to 2017 she was assigned to the Embassy of Italy in Tokyo, as First Commercial Secretary. On March 16th, 2017 she officially took up her duties as Consul of Italy at the Consulate of Italy in Detroit, responsible for the States of Indiana, Kentucky, Michigan, Ohio and Tennessee.