San Diego's nearly 70 year-old red sauce Italian restaurant Nicolosi's has relocated for the fourth time in its long history and will reopen this week in East County. Sicily-native Salvatore Nicolosi opened the original Nicolosi's as a bakery in 1952 in the Mission Hills neighborhood before moving it to 40th and El Cajon Boulevard in 1954.

In 1991, ownership moved Nicolosi's to Adobe Falls and Waring Roads because the Interstate 15 construction project developed through their former restaurant. Under third generation ownership, the restaurant moved for a third time to its last location at 7005 Navajo Road near Cowles Mountain in San Carlos. In 2020, a "ghost kitchen" outpost of Nicolosi's opened within the new Barrio Food Hub in Barrio Logan but closed soon after.