When I first visited Florence as a young whelp I was too much of a wuss to try the city's signature panini di lampredotto, a tripe sandwich sold from street stalls all over the city. Historically a workingman's sandwich, it was a cheap, high-protein way to fill up on the way to the olive orchards.

But it's maintained its appeal despite its filling: the abomasum, or a ruminant's fourth stomach, which resembles "bundles of dirty dishcloths" as the The Oxford Companion to Italian Food puts it, and can smell fairly miasmic if not properly cleaned. 

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Source: http://www.chicagoreader.com/