Michelangelo Buonarroti (1475–1564) was a master anatomist as well as anartistic genius. He dissected numerous cadavers and developed a profoundunderstanding of human anatomy. Among his best-known artworks are thefrescoes painted on the ceiling of the Sistine Chapel (1508–1512), in Rome.

Currently, there is some debate over whether the frescoes merely representthe teachings of the Catholic Church at the time or if there are other meaningshidden in the images. In addition, there is speculation regarding the image ofthe brain embedded in the fresco known as "The Creation of Adam," whichcontains anatomic features of the midsagittal and lateral surfaces of the brain.

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Source: http://onlinelibrary.wiley.com/